AI-Guided Multiscale Biomaterial Platform for Microbiome-Bone Marrow Axis Therapy
To develop an AI-integrated precision therapeutic platform for hematologic malignancies and bone marrow diseases by elucidating multiscale biomaterial interactions with the microbiome-bone marrow axis and establishing next-generation treatment technologies through AI-based prediction and design systems
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Model gut-blood-bone marrow axis for postbiotic signal effects on bone marrow environment
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Deploy membrane-based system for simultaneous anaerobic/aerobic conditions with selective metabolite diffusion while blocking bacteria and endotoxins
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Apply machine learning to correlate nanomaterial properties with cellular responses for optimal culture design
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Regulate cell-specific requirements through multiscale hierarchical structure control
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Ensure organoid reproducibility via AI-driven detection and automated parameter adjustment